{"id":1,"date":"2023-04-04T22:35:53","date_gmt":"2023-04-05T01:35:53","guid":{"rendered":"https:\/\/www.inicc.org\/site\/?p=1"},"modified":"2023-04-21T16:41:43","modified_gmt":"2023-04-21T19:41:43","slug":"1","status":"publish","type":"post","link":"https:\/\/www.inicc.org\/site\/2023\/04\/04\/1\/","title":{"rendered":"The impact of healthcare-associated infections on mortality in ICU in 37 Countries"},"content":{"rendered":"
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The impact of healthcare-associated infections on mortality in ICU: A prospective study in Asia, Africa, Eastern Europe, Latin America, and the Middle East<\/h4>\r\n
\u00a0<\/div>\r\n<\/header>\r\n
\u00a0<\/h5>\r\n
Abstract<\/h5>\r\n
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Background: <\/strong>The International Nosocomial Infection Control Consortium has found a high ICU mortality rate. Our aim was to identify all-cause mortality risk factors in ICU-patients.<\/p>\r\n

Methods: <\/strong>Multinational, multicenter, prospective cohort study at 786 ICUs of 312 hospitals in 147 cities in 37 Latin American, Asian, African, Middle Eastern, and European countries.<\/p>\r\n

Results: <\/strong>Between 07\/01\/1998 and 02\/12\/2022, 300,827 patients, followed during 2,167,397 patient-days, acquired 21,371 HAIs. Following mortality risk factors were identified in multiple logistic regression: Central line-associated bloodstream infection (aOR:1.84; P<.0001); ventilator-associated pneumonia (aOR:1.48; P<.0001); catheter-associated urinary tract infection (aOR:1.18;P<.0001); medical hospitalization (aOR:1.81; P<.0001); length of stay (LOS), risk rises 1% per day (aOR:1.01; P<.0001); female gender (aOR:1.09; P<.0001); age (aOR:1.012; P<.0001); central line-days, risk rises 2% per day (aOR:1.02; P<.0001); and mechanical ventilator (MV)-utilization ratio (aOR:10.46; P<.0001). Coronary ICU showed the lowest risk for mortality (aOR: 0.34;P<.0001).<\/p>\r\n

Conclusion: <\/strong>Some identified risk factors are unlikely to change, such as country income-level, facility ownership, hospitalization type, gender, and age. Some can be modified; Central line-associated bloodstream infection, ventilator-associated pneumonia, catheter-associated urinary tract infection, LOS, and MV-utilization. So, to lower the risk of death in ICUs, we recommend focusing on strategies to shorten the LOS, reduce MV-utilization, and use evidence-based recommendations to prevent HAIs.<\/p>\r\n<\/div>\r\n

\u00a0<\/h4>\r\n

Title:<\/h4>\r\n

Rosenthal VD, Yin R, Lu Y, Rodrigues C, Myatra SN, Kharbanda M, Valderrama-Beltran SL, Mehta Y, Daboor MA, Todi SK, Aguirre-Avalos G, Guclu E, Gan CS, Jim\u00e9nez-Alvarez LF, Chawla R, Hlinkova S, Arjun R, Agha HM, Zuniga-Chavarria MA, Davaadagva N, Basri MNM, Gomez-Nieto K, Aguilar-de-Moros D, Tai CW, Sassoe-Gonzalez A, Aguilar-Moreno LA, Sandhu K, Janc J, Aleman-Bocanegra MC, Yildizdas D, Cano-Medina YA, Villegas-Mota MI, Omar AA, Duszynska W, BelKebir S, El-Kholy AA, Alkhawaja SA, Florin GH, Medeiros EA, Tao L, Memish ZA, Jin Z. The impact of healthcare-associated infections on mortality in ICU: A prospective study in Asia,\u00a0Africa, Eastern Europe, Latin America, and the Middle East.<\/em> <\/strong>Am J Infect Control. 2022 Sep 6:S0196-6553(22)00658-7. doi: 10.1016\/j.ajic.2022.08.024. Epub ahead of print. PMID: 36075294.<\/p>\r\n

https:\/\/pubmed.ncbi.nlm.nih.gov\/36075294\/<\/a><\/p>\r\n

 <\/p>\r\n

 <\/p>\r\n","protected":false},"excerpt":{"rendered":"

The impact of healthcare-associated infections on mortality in ICU: A prospective study in Asia, Africa, Eastern Europe, Latin America, and the Middle East \u00a0 \u00a0 Abstract Background: The International Nosocomial Infection Control Consortium has found a high ICU mortality rate. Our aim was to identify all-cause mortality risk factors in ICU-patients. Methods: Multinational, multicenter, prospective […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"default","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[4,1],"tags":[],"class_list":["post-1","post","type-post","status-publish","format-standard","hentry","category-hai-rates","category-no-category"],"_links":{"self":[{"href":"https:\/\/www.inicc.org\/site\/wp-json\/wp\/v2\/posts\/1","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.inicc.org\/site\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.inicc.org\/site\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.inicc.org\/site\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.inicc.org\/site\/wp-json\/wp\/v2\/comments?post=1"}],"version-history":[{"count":4,"href":"https:\/\/www.inicc.org\/site\/wp-json\/wp\/v2\/posts\/1\/revisions"}],"predecessor-version":[{"id":984,"href":"https:\/\/www.inicc.org\/site\/wp-json\/wp\/v2\/posts\/1\/revisions\/984"}],"wp:attachment":[{"href":"https:\/\/www.inicc.org\/site\/wp-json\/wp\/v2\/media?parent=1"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.inicc.org\/site\/wp-json\/wp\/v2\/categories?post=1"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.inicc.org\/site\/wp-json\/wp\/v2\/tags?post=1"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}